If your four-year old shoves a bead up his nose, for no apparent reason, a toothpick works nicely for getting it out.
I know this because that's what I used last night. In the past (yes, sadly, this was not the first, or even the second or third time, I've had to do this), I learned quickly that a tweezer only sends the bead higher up into the nose. With a toothpick, I could slide it into the hole of the bead and then maneuver it out.
This is what I went to college for.